From Cells To Colonies: At What Levels Of Body Organization Does The 'Temperature-Size Rule' Apply?, Evol. & Dev.
(...) Evidence suggests that within organs, this "temperature-size rule" (TSR) may also apply to cell size with no change in numbers. So how closely do reductions in size and number of cells and other repeated structures correlate with size reduction at higher levels of organization? We examine this in the context of a proposal that size and/or number changes at various organizational levels are adaptive responses to temperature- and size-dependent oxygen supply. (...) We found that the size:number responses varied among cell types and among structures at different levels of organization (...).