Complexity Digest 2000.48

27-Nov-2000

For individual e-mail subscriptions go to Subscriptions.
Previous issue 2000.47 | Next issue 2000.49

  1. What Is A Moment? "Cortical" Sensory Integration Over A Brief Interval, PNAS Next Article Bookmark and Share

    Abstract: Recognition of complex temporal sequences is a general sensory problem that requires integration of information over time. We describe a very simple "organism" that performs this task, exemplified here by recognition of spoken monosyllables. The network's computation can be understood through the application of simple but generally unexploited principles describing neural activity. The organism is a network of very simple neurons and synapses; the experiments are simulations. The network's recognition capabilities are robust to variations across speakers, simple masking noises, and large variations in system parameters. The network principles underlying recognition of short temporal sequences are applied here to speech, but similar ideas can be applied to aspects of vision, touch, and olfaction. In this article, we describe only properties of the system that could be measured if it were a real biological organism. We delay publication of the principles behind the network's operation as an intellectual challenge: the essential principles of operation can be deduced based on the experimental results presented here alone. An interactive web site is available to allow readers to design and carry out their own experiments on the organism.

  2. AI and Simulation--Modeling the Emergence of Cooperation & Trust, Simulation Next Article Bookmark and Share

    Excerpts: "Last month 's column gave an historical perspective on the modeling and simulation of business and industrial firms. It ended with the suggestion that the next stage in these modeling efforts would require better ways to account for the human aspects of the countless interactions that take place continually within and among today 's enterprises. Optimal management of financial and physical resources hinges finally on the successful management of people. Perhaps the most important issue in business management is finding just the right balance between competition and cooperation within the manager 's own company as well as between that company and other companies.

    The firm is a network of its employees and its internal organizations. It lives in a greater network of markets, suppliers, customers, partners and competitors. Using agents is a natural way to model networks but most of the existing agent-based simulations employ homogeneous agents. The research reviewed above implies that a model of a firm as a network would only be interesting if the agents were heterogeneous enough to produce a heterarchy at the same time as they evolved toward cooperation through the action of strong reciprocity. This research into cooperation, competition, diversity and learning in organizations only suggests some of the problems that are still to be addressed in order to build practical simulations that will actually help the managers of real-world enterprises. (...)

    Cosmides and Tooby are Co-directors of the Center for Evolutionary Psychology at the University of California,Santa Barbara.For a look at their more current research,see http://www.psych.ucsb.edu/research/cep . Published papers by Samuel Bowles,Herbert Gintis and their colleagues may best be found starting from Bowles ' Website at http:://www-unix.oit.umass.edu/~bowles/.Some of their as yet unpublished working papers are available from the Santa Fe Institute at http://www.santafe.edu/sfi/publications/00wplist.html .For more about heterarchy and David Stark 's research,see http://www.sociology.columbia.edu/faculty/stark/.

    The following Websites also contain information pertinent to enterprise modeling as discussed in this and last month 's columns:


  3. Cultural Revolution In Whale Songs, Nature Next Article Bookmark and Share

    About thirty years ago it was recognized that Humpback whales are capable of elaborate songs lasting more than fifteen minutes, about five times longer than songs that humans remember to sing. Since then a number of researchers have tried to understand why they are doing this over and over again for a number of months during breeding season. During that time the songs -organized in well reproducible phrases and themes that even seem to "rhyme"- slowly evolve in a manner similar to human songs: variations are introduced, some phrases are shortened and dropped, new ones introduced etc. For the rest of the year, whales are manly busy traveling to the high latitude feeding grounds apparently forgetting about the songs. But once they are back in the breeding grounds the singers all start singing again the same songs right where they left them at the end of the previous season. Because of the temporal coincidence of breeding and singing it was speculated that females are attracted to the best singers. Careful experiments using playback of the latest songs showed, however, that instead of flocking around the singers the females rather avoid them and take off with the non-singing jocks among the whales. Are the songs perhaps some form of Humpback Whale Blues?

    Other speculations that songs are used as some sort long-range sonar used by males to locate other whales is even less founded by empirical evidence. While blue whales produce low frequency sounds that can be heard over long distances humpback whales don't seem to make any effort to be heard over long ranges by for instance singing at a depth that is optimized for underwater sound propagation.

    Just like human music does not give a direct evolutionary advantage to the singer but is rather an expression of culture, Rendell & Whitehead have argued that humpback whale songs are an expression of whale culture and transmitted by social learning. Independently Noad et al came to the same conclusion in a striking observation as a result of listening to more than a thousand hours of humpback whale songs: They found evidence for a "cultural revolution" in musical style. Within a few years all singers on the East coast of Australia picked up a song imported by two initial traveling minstrel singers from the West coast. The radical difference between the two styles is evident even to the non-expert. Michael Noad was kind enough to make a sound example, illustrating the difference, available to ComDig. Click here to listen to the sound example. It is a

    "(...) phrase from the first theme of the old and new songs of our study (you can see where one stops and the other starts by the difference in the background noise levels as well as the sounds being obviously different). The old song is simply a series of five 'down-up moans', the new phrase is a 'long descending moan' and a 'level growl'." (M. Noad)

    This rapid spread among the whole population cannot be explained without the presence of cultural transmission. In a complex systems framework this phenomenon could be understood as a consequence of a "small world" network structure among the humpback whale singers (see Mayer-Kress & Porter).


  4. Beyond Game Theory, WorldLink Next Article Bookmark and Share

    While game theory works well for simple zero-sum situations, its powerful extension, the theory of moves, can offer valuable insights into the dynamic nature of conflicts.

    If it really is your friend's birthday, then buying the expensive seats will go down better than just an evening at the bar.

    But if it's not his birthday, then while your friend will be delighted with the unexpected treat, your bank manager might not be.

    And on the face of it, this is also what happened in the Cuban missile crisis, where the thermonuclear equivalent of driving over the edge forced both sides into a draw.

    And the answer emerging from his research takes the form of a powerful extension of game theory, now attracting much interest among experts in conflict resolution.

    As its name suggests, ToM allows the reactions of players to evolving situations to be traced in detail.

    In a series of intriguing papers, Brams and his co-workers have used ToM to analyse a whole raft of conflicts, from game-theoretic classics like the Cuban missile crisis to complex battles of will such as that between the Polish Communist party and the trade union movement Solidarity in the early 1980s.

    Seen from the standpoint of standard game theory, the response of the Nixon administration to the outbreak of the conflict was terrifyingly reckless.

    But what the White House chose to do shocked many: it upped the stakes, putting all US military forces on global nuclear alert.

    According to Brams, the reason lies in the way the conflict evolves into different states, according to the starting positions of the players - a feature better captured by ToM than by standard game theory.

    At root, this long-running conflict is between the Irish Republican Army (IRA) - determined to make Northern Ireland part of the Irish republic - and the British government and Ulster Unionists, who are determined to see the province remain in the UK.

    So why did the British government agree in 1998 to the power-sharing accord of the Good Friday agreement, when the IRA had already called a cease-fire?

    Summarized with Copernic Summarizer


  5. Chaos Theory Tells Pilots When To Take A Break, New Scientist Next Article Bookmark and Share

    Excerpt: "Airline pilots and air traffic controllers who are too tired to work safely could soon be identified automatically, thanks to a Japanese monitoring system that analyses voice patterns for signs of fatigue.

    "Our system is able to detect tiredness in test subjects 10 to 20 minutes before the subjects themselves notice it," says Kakuichi Shiomi, chief researcher at the Electronic Navigation Research Institute near Tokyo, which developed the system.

    Human error currently accounts for around 80 per cent of all air accidents worldwide. "Crew fatigue is a very real problem, especially on long-haul flights crossing many time zones," says Shiomi.

    Called a fatigue and drowsiness predictor, the system uses the mathematics of chaos theory to compare changes in the voices of wide-awake, alert people with those of fatigued people. The change is known to be related to a drop in blood pressure when people are tired--but it is very subtle. So Shiomi's team at ENRI, a division of the Japanese Ministry of Transport, had to come up with a way of analysing speech that brings these small changes into sharp relief."


  6. Gamma Oscillations and Object Processing in the Infant Brain, Science Next Article Bookmark and Share

    Abstract: An enduring controversy in neuroscience concerns how the brain "binds" together separately coded stimulus features to form unitary representations of objects. Recent evidence has indicated a close link between this binding process and 40-hertz (gamma-band) oscillations generated by localized neural circuits. In a separate line of research, the ability of young infants to perceive objects as unitary and bounded has become a central focus for debates about the mechanisms of perceptual development. Here we demonstrate that binding-related 40-hertz oscillations are evident in the infant brain around 8 months of age, which is the same age at which behavioral and event-related potential evidence indicates the onset of perceptual binding of spatially separated static visual features.

  7. Novel Vaccine Protects Monkeys From Ebola Infection, NIAID/Science Daily Next Article Bookmark and Share

    Excerpts: Few viruses are more feared than Ebola virus, the deadly microbe that periodically attacks African villages and kills up to 90 percent of those it infects. Although other viral diseases claim more lives each year, the ruthless efficiency and nightmarish symptoms of Ebola virus make a vaccine against this killer an important goal of scientists. Now, as described in the November 30 issue of Nature, a team of researchers led by scientists from the National Institutes of Health (NIH) has developed a novel vaccine that prevents Ebola virus infection in monkeys. All four vaccinated monkeys were completely protected from a lethal dose of the virus. This study describes the first primate model of immune protection against Ebola virus, a model that may allow scientists to rationally design a vaccine that prevents this dreaded disease in humans.

    "Doctors have essentially been helpless against Ebola virus," says Gary Nabel, M.D., Ph.D., director of the Dale and Betty Bumpers Vaccine Research Center (VRC) at the NIH and a lead author of the study. "We have not known if immunity to the virus exists or what parts of the immune response are important. Our studies show that animals can launch an effective immune response against Ebola virus, and we can use knowledge of this response to design a vaccine that protects non-human primates from infection. Although much more work needs to be done, we hope this moves us closer to new vaccines and treatments for Ebola and other viruses."

    Ebola virus kills quickly, giving the body little time to launch an effective immune response. Infected individuals suffer severe pain, high fever and extensive internal bleeding. Although the virus periodically strikes humans, scientists do not know where it resides in nature between outbreaks. (…)

    Dr. Nabel and colleagues had previously tested genetic Ebola vaccines-strands of DNA containing genes that encode Ebola virus proteins-for their ability to induce immune responses in rodents and to protect against disease. Unlike traditional vaccines, typically made from viral proteins, DNA vaccines more closely mimic virus infection because they enter a cell and use that cell's machinery to manufacture new viral proteins. Researchers believe this strategy might better trick the immune system into thinking a real virus infection has occurred. (…)

    Armed with this promising new vaccine, the researchers tested a novel prime-boost immunization strategy on eight monkeys. Four monkeys received the three-strain Ebola virus DNA vaccine and then were injected with the Ebola-adenovirus booster. The other four monkeys received placebo immunizations. All four vaccinated monkeys launched strong anti-Ebola immune responses and survived a subsequent exposure to lethal doses of Ebola Zaire virus. Three of these monkeys showed no sign of viral infection, whereas a slight, temporary increase in Ebola virus in the blood of one of the vaccinated monkeys disappeared after one week. More than six months after infection, the four monkeys remained symptom-free with no detectable virus in the blood.

    The researchers are continuing their efforts. "We of course want to test the multivalent vaccine for effectiveness against all three strains of Ebola virus," says Dr. Sullivan, "but we also need to look more closely at the immune response induced by these vaccines so we can nail down what is needed for protection." By studying the mechanism of protection induced by the vaccine, they can determine what combination of antibodies, helper T cells and killer T cells defend the monkeys against infection. They then hope to use this information to rationally design new vaccines and antiviral treatments for humans.


  8. Regulation Of Immune System Memory, U.Iowa/Science Daily Next Article Bookmark and Share

    Excerpts: If a person's immune system successfully fights off an infection, not only does that person recover, but they also acquire immunity against re-infection by that same pathogen. The ability of the immune system to remember pathogens it has already defeated, and to respond rapidly and effectively to them during future exposures, is the basis of vaccination strategies. (…)

    "It was thought that the only role for these molecules was to enable T cells to directly or indirectly destroy infected cells," Harty said. "We have identified another role for the molecules, as regulators that control how many T cells are generated in response to infection and how many of these cells survive and contribute to immune memory."

    Harty added that this work reinforces a long-standing notion about the immune system, that it is able to use the same molecule for different functions.

    "The immune system has learned to use and modify existing systems to do the jobs required to fight off infections," Harty said. (…)

    Until very recently, researchers evaluating the nature and strength of an immune response focused on antibody production. Antibodies are molecules generated by the immune system to help fight infection. They are easy to detect and quantify. In the last five years, however, there has been a revolution in scientists' ability to identify, count and assess the function of antigen-specific T cells with high precision. Measuring these cells gives a much more accurate assessment of an immune response to either an infection or a vaccine.

    "I suspect that in the next few years we will be able to use these tools to assess how good human vaccines actually are," Harty said.

    In the current studies, Harty and his colleagues used these measuring techniques and previous research to set about carefully measuring the levels of T cells during different stages of infection. Investigating the immune response in mice, genetically engineered to lack either or both molecules, the researchers elucidated the regulatory roles of perforin and interferon gamma.

    The mice were infected with Listeria monocytogenes, a bacterial pathogen that causes food-borne infections in humans. The studies showed that perforin controls the total number of T cells initially generated in response to a pathogen, and interferon gamma controls the process by which most of those cells are eliminated after the infection is cleared. Interferon gamma also affects which parts of the pathogen cause the immune system to respond.

    The roles of these molecules did not change when the researchers repeated the experiments using a virus as the infecting agent even though viruses and bacteria interact with the host animal in very different ways during an infection.

    "This is very basic research aimed at understanding how this very precisely orchestrated expansion and decline, and memory phase of the immune system is controlled," Harty said. "Understanding how the basic biology of the system is regulated provides insight into how we might manipulate the system. In the case of these studies, the ultimate goal would be to learn how to manipulate the levels of T cell memory, which could result in better, more effective vaccinations."

    Autoimmune diseases result from inappropriate activation of certain T cell subsets, which recognize self-antigens as opposed to pathogen antigens. Understanding how T cells are regulated could also help scientists understand and possibly treat autoimmune conditions.


  9. Close Encounters: Good, Bad, and Ugly, Science Next Article Bookmark and Share

    Summary: Microbiologists often focus on one organism and its relationship to its host at one point in time. But viewed in light of evolution, host-parasite relationships range from deadly to helpful, depending on the communication between them. At a meeting here last month of virologists, bacteriologists, parasitologists, and molecular biologists--each dealing with different microorganisms in distinct ways--researchers lamented that evolution is often considered outside the bailiwick of microbiologists, particularly those studying infectious diseases.

    Copernic Summary: As an unlikely mix of virologists, bacteriologists, parasitologists, and molecular biologists--each dealing with different microorganisms in distinct ways--discussed their work, they came to better appreciate evolutionary biologist Theodosius Dobzhansky's observation that nothing makes sense except in the light of evolution.

    But stepping back to view the whole range of relationships between microbes and their hosts reveals that "there's a spectrum [of microorganisms] from the highly virulent to barely pathogenic," says Stephen Beverley, a molecular parasitologist at Washington University in St. Louis.

    Stanford University molecular biologist Sharon Long has been exploring a cooperative interaction that might once have been an adversarial one: the symbiosis between a plant and its nitrogen-fixing bacteria.

    As the plant becomes an ally in promoting this infection, it builds a tunnel of extracellular material around the dividing bacteria and allows them entry into some of its cells.

    Take Leishmania, a protozoan parasite that now infects some 12 million people worldwide, often causing disfiguring disease and sometimes death.


  10. Complexity and Fragility in Ecological Networks, SFI Working Papers Next Article Bookmark and Share

    Abstract: A detailed analysis of three species-rich ecosystem food webs has shown that they display scale-free distributions of connections. Such graphs of interaction are in fact shared by a number of biological and technological networks, which have been shown to display a very high homeostasis against random removals of nodes. Here we analyze the response of these ecological graphs to both random and selective perturbations (directed to most connected species). Our results suggest that ecological networks are extremely robust against random removal but very fragile when selective attacks are used. These observations can have important consequences for bio-diversity dynamics and conservation issues, current estimations of extinction rates and the relevance and definition of keystone species.

  11. Ancient South African Soils Point To Early Terrestrial Life, Science Daily Next Article Bookmark and Share

    Excerpts: "Remnants of organic matter in ancient soil more than 2.6 billion years old may be the earliest known evidence for terrestrial life, according to a team of Penn State astrobiologists.

    "Our work shows that the organic matter in this soil very probably represents remnants of microbial mats that developed on the soil surface between 2.6 and 2.7 billion years ago," says Dr. Hiroshi Ohmoto, professor of geochemistry and director of The Penn State Astrobiology Center. "This places the development of terrestrial biomass more than 1.4 billion years earlier than previously reported." Evidence that microorganisms flourished in the oceans since at least 3.8 billion years ago exists, but when these microorganisms colonized on land is not clear. The oldest undisputed remnants of terrestrial biomass have been 1.2 billion-year-old microfossils found in Arizona.

    Examining samples taken from Mpumalanga Province, South Africa, using a variety of geochemical methods, the researchers report in this week's issue of Nature, that a paleosol dating to between 2.6 and 2.7 billion years ago contains organic carbon that was neither created by high temperature fluids nor is the remnant of later petroleum migration, but is in-situ biological in origin. (…)

    In the lower portion of the paleosol, things are less clear because the effects of seeping water and the dissolution and precipitation of materials suggest some decomposition. While identifying the organism in the microbial mats is difficult, the researchers are certain that they were not photosynthetic sulfur bacteria as there is no sulfur present. Photosynthetic blue-green algae, however, are a likely possibility for the mat formation because the ancient remnants have nearly identical carbon isotope ratios as modern blue-green algal mats in fresh water.

    The researchers are also certain that the mats formed on land, not in the oceans, because the carbon isotope values for the carbon in the paleosol are distinctly different from the organic carbon found in marine sedimentary rock.

    "Although terrestrial bacterial communities were predicted by previous researchers, this is, to our knowledge, the first study presenting several lines of evidence for an extensive development of microbial mats on soil surfaces in the Archaean," says Ohmoto. "Our finding may then imply that an ozone shield developed before 2.6 billion years ago.

    "The ozone shield would have protected land-based biological forms from the effects of cosmic radiation. Development of the ozone shield requires an oxygen-rich atmosphere. Our finding of ancient biomats on land is an important addition to a growing line of evidence suggesting that the rise of atmopsheric oxygen took place more than 2.6 billion years ago." "


  12. Climate Science "In Play", UNFCCC Next Article Bookmark and Share

    Summary: Without action to limit greenhouse gas emissions the Earth’s climate will warm at a rate unprecedented in the last 10,000 years: If actions are not taken to reduce the projected increase in greenhouse gas emissions, the Earth’s climate is projected to change at a rate unprecedented in the last 10,000 years with adverse consequences for society, undermining the very foundation of sustainable development.

    Policymakers are faced with responding to the risks posed by anthropogenic emissions of greenhouse gases in the face of significant scientific uncertainties. They may want to consider these uncertainties in the context that climate-induced environmental changes cannot be reversed quickly, if at all, due to the long time scales (decades to millennia) associated with the climate system. Decisions taken during the next few years may limit the range of possible policy options in the future because high near-term emissions would require deeper reductions in the future to meet any given target concentration. Delaying action would increase both the rate and the eventual magnitude of climate change, and hence adaptation and damage costs.

    Policymakers will have to decide to what degree they want to take precautionary measures to limit anthropogenic climate change by mitigating greenhouse gas emissions and enhancing the resilience of vulnerable systems by means of adaptation. Uncertainty does not mean that a nation or the world community cannot position itself better to cope with the broad range of possible climate changes or protect against potentially costly future outcomes. Delaying such measures may leave a nation or the world poorly prepared to deal with adverse changes and may increase the possibility of irreversible or very costly consequences. Options for mitigating change or adapting to change that can be justified for other reasons today and make society more flexible or resilient to anticipated adverse effects of climate change appear particularly desirable.

    • Climate Science "In Play", Robert T. Watson, Chair Of The Intergovernmental Panel On Climate Change(IPCC), Keynote Speech At The Sixth Conference Of The Parties To The United Nations Framework Convention On Climate Change (UNFCCC), November 13, 2000


  13. An Electoral Butterfly Effect, Nature Next Article Bookmark and Share

    Robert Sinclair of the University of Alberta and colleagues report in a Brief Communication this week that some Canadian shoppers made a crucial mistake in simulated voting, for a Canadian prime minister, of exactly the type that may have given Pat Buchanan votes intended for Al Gore. Of 53 people using the double-column butterfly ballot, four made mistakes; three of these involved voting for the candidate in the wrong column. By contrast, a similarly sized group of shoppers given a simpler, single-column ballot made no mistakes.

    "Here we show that not only is the double-column butterfly ballot more confusing than a single-column ballot, but that it also appears to cause systematic errors in voting which call into question the validity of the results from Palm Beach County in the 2000 United States presidential election. To test whether the butterfly ballot format is likely to confuse voters, we asked Canadian college students to vote for a prime minister of Canada on the day after the presidential election in the United States (…) "

    • An Electoral Butterfly Effect, Robert C. Sinclair, Melvin M. Mark, Sean E. Moore, Carrie A. Lavis, Alexander S. Soldat, Nature Prepublication, 408, 665-666; 2000


  14. Problems of Individual Emergence, Conference Announcement Next Article Bookmark and Share

    Biannually a conference is held in Amsterdam to consider, in a free and generous spirit, questions that prove fundamental to research (in new as well established as areas). These prestigious meetings are entitled: "Problems of ". The 12th meeting, in 2001, will explore Problems of Individual Emergence.

    Individual emergence refers to the reverse of collective emergence, i.e. the phenomenon that the sum of the parts may be more than the whole. The aim of the conference is to study what permits parts to be or become more than any whole constituted of these parts.

    Individuals in composites or collectives often develop new or improved values, abilities and properties they are not otherwise able to develop. That such qualities sometimes complement, or even conflict with, each other appears due to the possibility that individuals are part of many collectives at the same time.

    Qualities defined by composites or collectives apparently include the ability to behave intelligently, take initiatives, be compassionate, use and develop languages, show observer-effects in experiments-as may be argued on the basis of their opposites, i.e. people on occasion behaving as wolves to each other (homo homini lupus).

    • Problems of Individual Emergence, April 16-20, 2001 -Amsterdam, UK Cybernetics Society, Systeemgroep Nederland, Lincoln Research Centre, Center for Innovation and Cooperative Technology of the University of Amsterdam
    • Contributed by Marshall Clemens


  15. Links & Snippets Next Article Bookmark and Share

    1. 1 Changes In Deep-Water Formation During The Younger Dryas, Nature Next Article Bookmark and Share

      Excerpt: Here we present such an analysis of the large fluctuations in atmospheric 14C concentrations, of unclear origin, that occurred during the Younger Dryas cold period. We (…) model past production rates of radionuclides, and find that the largest part of the fluctuations in atmospheric radiocarbon concentrations can be attributed to variations in production rate. The residual difference between measured 14C concentrations and those modeled using the 10Be record can be explained with an additional change in the carbon cycle, most probably in the amount of deep-water formation.


    2. 2 Triggering Of Earthquake Aftershocks By Dynamic Stresses, Nature Next Article Bookmark and Share

      Excerpt: It is thought that small 'static' stress changes due to permanent fault displacement can alter the likelihood of, or trigger, earthquakes on nearby faults. Many studies of triggering in the near-field, particularly of aftershocks, rely on these static changes as the triggering agent and consider them only in terms of equivalent changes in the applied load on the fault. Here we report a comparison of the aftershock pattern of the moment magnitude Mw = 7.3 Landers earthquake, not only with static stress changes but also with transient, oscillatory stress changes transmitted as seismic waves (that is, 'dynamic' stresses). (...)


    3. 3 Visualization of Cooperation in the Construction of a Monolithic Building, Simulation Next Article Bookmark and Share

      When a monolithic construction is being erected, a strict regime must be followed on the thickness of a concrete layer and on the layer's solidification time. This regime can only be satisfied if all the cooperating ele-ments (a concrete mixer, a crane, gangs working at the top of a building) har-monize. Assuming constant parameters of the co-operating elements (but no constant increase of the construction within a 24-hour period is required), this paper presents the CoMB program, which dynamically visualizes this harmonization and reports the percentage of usage of co-operating elements. A didactic aspect of such a visualisation is outlined.


    4. 4 This Campus Is Being Simulated, NYTimes Next Article Bookmark and Share

      Excerpt: "While it has become a truism that the Internet will revolutionize higher education, there is some confusion as to exactly whose experience is likely to be transformed. GEN expects to do about 90 percent of its business with adult learners, who would be taking noncredit classes, and the remaining 10 percent with high school students, who would, or so the theory goes, receive Advanced Placement credit for a GEN class. Only somewhere down the road would GEN be colonizing the campus itself. At least in the immediate future, the elite institutions will function principally as producers, rather than consumers, in the online marketplace."


    5. 5 Stem Cells Hear Call of Injured Tissue, Science Next Article Bookmark and Share

      In animal models, injected stem cells travel to tissue injured by stroke, Alzheimer's-like plaques, contusions, or spinal cord bruises, sometimes traversing long distances. Several teams reported these surprising results this month at the Society for Neuroscience annual meeting. No one knows exactly how stem cells detect these different kinds of damage, but researchers hope that the cells' migratory powers can be harnessed to either replace dead tissue or deliver therapeutics right where they're needed.


    6. 6 Book Review, Letter to the Editor Bookmark and Share

      A NAME="15.6">

      Gottfried,

      Item for Complexity Digest:

      I recently came across an excellent review of two of Richard Lewontin's recent books. The books, "It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions" and "The Triple Helix: Gene, Organism and Environment" present a complexity view of the present state of biological knowledge. The case for complexity, and the fascination of its subtleties,is well presented by the reviewer, Rob Dorit of Yale.

      The review is published in September-October 2000 issue of American Scientist, and is on-line at

      http://www.amsci.org/amsci/bookshelf/Leads00/Dorit.html.


Also available in: Simple HTML format | TXT format | TXT format with links | Print