Complexity Digest 2005.05 - 02
Malaria Vaccines: Back to the Future?, Science
Excerpts: Malaria is the scourge of many developing countries, particularly those in sub-Saharan Africa, claiming several million lives each year. Researchers have struggled for decades to make a successful subunit or attenuated whole-organism vaccine but with limited success. Factors that have hampered the development of a subunit vaccine include the complexity of the malaria life cycle, the wide variety of immune response induced by the malaria parasite, and an incomplete knowledge of protective immunity.
- Source: Malaria Vaccines: Back to the Future?
[ http://www.sciencemag.org/cgi/content/full/307/5709/528 ], A. P. Waters, M. M. Mota, M. R. van Dijk, C. J. Janse, Science 528-530, 05/01/28