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Complexity Digest 2008.48 - 10.01
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27-Nov-2008

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Cell Biology: Nuclear Order Out Of Chaos, Nature
 









Excerpts: How cells build their internal structures remains one of the central
mysteries in cell biology. If the cell nucleus is anything to go by, stochastic
assembly and self-organization seem to be key.(...) How Cajal bodies, and indeed
all other nuclear bodies, are formed and maintained without membrane boundaries
has been a puzzle. Two fundamentally different models have been considered. One
idea - akin to the bookshelf-assembly strategy - is that Cajal-body proteins
bind to scaffold proteins in an orderly manner to gradually build up the
structure. (...).
Source: Cell Biology: Nuclear Order Out Of Chaos[
http://www.nature.comnature/journal/v456/n7220/full/456333a.html ], Tom Misteli,
DOI: 10.1038/456333a, Nature 456, 333-334, 08/11/20

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