Modular Random {Boolean} Networks

TitleModular Random {Boolean} Networks
Publication TypeJournal Article
Year of Publication2011
AuthorsPoblanno-Balp}, R{, Gershenson, C
JournalArtificial Life
Volume17
Pagination331–351
Abstract

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be modular. In this work, we extend classical RBNs to define modular RBNs. Statistical experiments and analytical results show that modularity has a strong effect on the properties of RBNs. In particular, modular RBNs have more attractors and are closer to criticality when chaotic dynamics would be expected, compared to classical RBNs.

URLhttp://arxiv.org/abs/1101.1893
DOI10.1162/artl_a_00042